{"id":6717,"date":"2025-12-09T01:28:06","date_gmt":"2025-12-09T01:28:06","guid":{"rendered":"https:\/\/bristishpharmacy.co.uk\/?post_type=product&#038;p=6717"},"modified":"2026-09-16T10:31:40","modified_gmt":"2026-09-16T10:31:40","slug":"oxycontin-20mg","status":"publish","type":"product","link":"https:\/\/bristishpharmacy.co.uk\/nl\/shop\/oxycontin-20mg\/","title":{"rendered":"OxyContin 20mg"},"content":{"rendered":"<h1>\u00a0<\/h1>\n<div class=\"container\">\n<div id=\"model-response-message-contentr_dd90e3c104cabb09\" class=\"markdown markdown-main-panel md-content enable-luminous-fast-follows enable-updated-hr-color stronger tutor-markdown-rendering\" dir=\"ltr\" aria-live=\"polite\">\n<h3 data-path-to-node=\"3\">Clinical Monograph: OxyContin 20 mg (Oxycodone HCl Extended-Release)<\/h3>\n<div class=\"attachment-container search-images\">\n<div class=\"image-container spark-licensed-center hide-from-message-actions ng-star-inserted\" data-full-size-image-uri=\"https:\/\/oidaresourcesimages-cdn-endpoint-duhwc2gse6gdbng7.a01.azurefd.net\/public\/full\/3a836534-b478-4c2e-b589-ecc6395e70ba.jpeg\">\n<div class=\"overlay-container hero-overlay-container ng-star-inserted\"><button class=\"image-button ng-star-inserted\"><img fetchpriority=\"high\" decoding=\"async\" class=\"spark-licensed-landscape hero-image loaded\" src=\"https:\/\/encrypted-tbn0.gstatic.com\/images?q=tbn:ANd9GcRx4mpW0jE7385blJMnp1RY_5vhdk2-gHpLWacQsw9BX14PH59WFh89Ui4&amp;s=10\" alt=\"OxyContin 20 mg controlled-release packaging, AI generated\" width=\"485\" height=\"339\" \/><\/button><\/p>\n<div class=\"hero-caption-row ng-star-inserted\">\n<div class=\"caption gds-extended-caption hero-caption ng-star-inserted\" aria-hidden=\"true\">OxyContin 20 mg controlled-release packaging. <span class=\"ng-star-inserted\">Source: OIDA Image Collection &#8211; Johns Hopkins University<\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<h2 data-path-to-node=\"5\">1. Classification and Chemical Overview<\/h2>\n<p data-path-to-node=\"6\">Oxycodone is a semi-synthetic, pure opioid agonist derived from the opium alkaloid thebaine. Chemically designated as (5$\\alpha$)-4,5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one hydrochloride, it belongs to the phenanthrene derivative class. Under the Anatomical Therapeutic Chemical (ATC) classification system, oxycodone is indexed under N02AA05.<\/p>\n<p data-path-to-node=\"7\">OxyContin 20 mg is formulated as an extended-release (prolonged-release) film-coated tablet containing 20 mg of oxycodone hydrochloride (equivalent to 17.93 mg free oxycodone base). Modern formulations incorporate abuse-deterrent properties designed to resist crushing, breaking, or dissolving into a injectable gel. Globally, OxyContin is classified as a strictly controlled substance (e.g., Schedule II under the US Controlled Substances Act; Class B \/ Schedule 2 Controlled Drug in the UK) and is available strictly as a Prescription Only Medicine (POM).<\/p>\n<h2 data-path-to-node=\"8\">2. Mechanism of Action and Pharmacodynamics<\/h2>\n<p data-path-to-node=\"9\">Oxycodone acts primarily as a full agonist at central and peripheral <span class=\"math-inline\" data-math=\"\\mu\" data-index-in-node=\"69\"><span class=\"katex\"><span class=\"katex-html\" aria-hidden=\"true\"><span class=\"base\"><span class=\"mord mathnormal\">\u03bc<\/span><\/span><\/span><\/span><\/span>-opioid receptors, with lesser affinity for <span class=\"math-inline\" data-math=\"\\kappa\" data-index-in-node=\"116\"><span class=\"katex\"><span class=\"katex-html\" aria-hidden=\"true\"><span class=\"base\"><span class=\"mord mathnormal\">\u03ba<\/span><\/span><\/span><\/span><\/span>&#8211; and <span class=\"math-inline\" data-math=\"\\delta\" data-index-in-node=\"128\"><span class=\"katex\"><span class=\"katex-html\" aria-hidden=\"true\"><span class=\"base\"><span class=\"mord mathnormal\">\u03b4<\/span><\/span><\/span><\/span><\/span>-opioid receptors:<\/p>\n<ul data-path-to-node=\"10\">\n<li>\n<p data-path-to-node=\"10,0,0\"><b data-path-to-node=\"10,0,0\" data-index-in-node=\"0\"><span class=\"math-inline\" data-math=\"\\mu\" data-index-in-node=\"0\"><span class=\"katex\"><span class=\"katex-html\" aria-hidden=\"true\"><span class=\"base\"><span class=\"mord mathnormal\">\u03bc<\/span><\/span><\/span><\/span><\/span>-Opioid Receptor Activation:<\/b> Binds to G-protein-coupled <span class=\"math-inline\" data-math=\"\\mu\" data-index-in-node=\"59\"><span class=\"katex\"><span class=\"katex-html\" aria-hidden=\"true\"><span class=\"base\"><span class=\"mord mathnormal\">\u03bc<\/span><\/span><\/span><\/span><\/span>-opioid receptors located on presynaptic and postsynaptic membranes in the central nervous system (brainstem, locus coeruleus, periaqueductal gray) and spinal cord dorsal horn.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"10,1,0\"><b data-path-to-node=\"10,1,0\" data-index-in-node=\"0\">Intracellular Signaling:<\/b> Inhibits adenylyl cyclase activity, decreases intracellular cyclic AMP (<span class=\"math-inline\" data-math=\"\\text{cAMP}\" data-index-in-node=\"97\"><span class=\"katex\"><span class=\"katex-html\" aria-hidden=\"true\"><span class=\"base\"><span class=\"mord text\"><span class=\"mord\">cAMP<\/span><\/span><\/span><\/span><\/span><\/span>), hyperpolarizes neuronal membranes via inwardly rectifying potassium channels, and blocks presynaptic voltage-gated N-type calcium channels.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"10,2,0\"><b data-path-to-node=\"10,2,0\" data-index-in-node=\"0\">Analgesic Inhibition:<\/b> Suppresses the presynaptic release of nociceptive neurotransmitters (substance P, glutamate, calcitonin gene-related peptide), dampening pain signal transmission along spinothalamic pathways and altering central pain perception.<\/p>\n<\/li>\n<\/ul>\n<p data-path-to-node=\"11\">Additional pharmacodynamic effects include central respiratory center depression, sedation, miosis, cough suppression, smooth muscle spasm, reduced gastrointestinal motility, and physical dependence.<\/p>\n<h2 data-path-to-node=\"12\">3. Approved Clinical Indications and Dosing Scope<\/h2>\n<p data-path-to-node=\"13\">Licensing for OxyContin 20 mg includes:<\/p>\n<ul data-path-to-node=\"14\">\n<li>\n<p data-path-to-node=\"14,0,0\"><b data-path-to-node=\"14,0,0\" data-index-in-node=\"0\">Severe Chronic Pain:<\/b> Management of severe pain requiring daily, continuous, long-term opioid treatment where alternative treatment options (e.g., non-opioid analgesics or immediate-release opioids) are inadequate.<\/p>\n<\/li>\n<\/ul>\n<p data-path-to-node=\"15\"><i data-path-to-node=\"15\" data-index-in-node=\"0\">Dosing &amp; Administration Regimen:<\/i><\/p>\n<ul data-path-to-node=\"16\">\n<li>\n<p data-path-to-node=\"16,0,0\"><b data-path-to-node=\"16,0,0\" data-index-in-node=\"0\">12-Hour Dosing Interval:<\/b> Administered orally every 12 hours. Dosing must be individually titrated based on pain severity and prior patient opioid exposure.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"16,1,0\"><b data-path-to-node=\"16,1,0\" data-index-in-node=\"0\">Administration Integrity:<\/b> Tablets must be swallowed whole with sufficient water and <b data-path-to-node=\"16,1,0\" data-index-in-node=\"84\">never<\/b> pre-soaked, crushed, chewed, split, or dissolved. Tampering with the extended-release matrix compromises controlled delivery, leading to rapid drug release (&#8220;dose dumping&#8221;) and potential fatal overdose.<\/p>\n<\/li>\n<\/ul>\n<h2 data-path-to-node=\"17\">4. Pharmacokinetic Profile and Metabolic Fate<\/h2>\n<ul data-path-to-node=\"18\">\n<li>\n<p data-path-to-node=\"18,0,0\"><b data-path-to-node=\"18,0,0\" data-index-in-node=\"0\">Absorption:<\/b> Exhibits biphasic absorption characteristics with an initial prompt release followed by gradual controlled release over 12 hours. Absolute oral bioavailability ranges from 60% to 87%. Peak plasma concentrations (<span class=\"math-inline\" data-math=\"C_{max}\" data-index-in-node=\"224\"><span class=\"katex\"><span class=\"katex-html\" aria-hidden=\"true\"><span class=\"base\"><span class=\"mord\"><span class=\"mord mathnormal\">C<\/span><span class=\"msupsub\"><span class=\"vlist-t vlist-t2\"><span class=\"vlist-r\"><span class=\"vlist\"><span class=\"\"><span class=\"sizing reset-size6 size3 mtight\"><span class=\"mord mtight\"><span class=\"mord mathnormal mtight\">ma<\/span><span class=\"mord mathnormal mtight\">x<\/span><\/span><\/span><\/span><\/span><span class=\"vlist-s\">\u200b<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span>) occur within 3 to 4.5 hours (<span class=\"math-inline\" data-math=\"T_{max}\" data-index-in-node=\"262\"><span class=\"katex\"><span class=\"katex-html\" aria-hidden=\"true\"><span class=\"base\"><span class=\"mord\"><span class=\"mord mathnormal\">T<\/span><span class=\"msupsub\"><span class=\"vlist-t vlist-t2\"><span class=\"vlist-r\"><span class=\"vlist\"><span class=\"\"><span class=\"sizing reset-size6 size3 mtight\"><span class=\"mord mtight\"><span class=\"mord mathnormal mtight\">ma<\/span><span class=\"mord mathnormal mtight\">x<\/span><\/span><\/span><\/span><\/span><span class=\"vlist-s\">\u200b<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span>) post-ingestion.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"18,1,0\"><b data-path-to-node=\"18,1,0\" data-index-in-node=\"0\">Distribution:<\/b> Widely distributed throughout body tissues following systemic absorption (<span class=\"math-inline\" data-math=\"V_d \\approx 2.6\\text{ L\/kg}\" data-index-in-node=\"88\"><span class=\"katex\"><span class=\"katex-html\" aria-hidden=\"true\"><span class=\"base\"><span class=\"mord\"><span class=\"mord mathnormal\">V<\/span><span class=\"msupsub\"><span class=\"vlist-t vlist-t2\"><span class=\"vlist-r\"><span class=\"vlist\"><span class=\"\"><span class=\"sizing reset-size6 size3 mtight\"><span class=\"mord mathnormal mtight\">d<\/span><\/span><\/span><\/span><span class=\"vlist-s\">\u200b<\/span><\/span><\/span><\/span><\/span><span class=\"mrel\">\u2248<\/span><\/span><span class=\"base\"><span class=\"mord\">2.6<\/span><span class=\"mord text\"><span class=\"mord\">\u00a0L\/kg<\/span><\/span><\/span><\/span><\/span><\/span>). Plasma protein binding is relatively low (~38% to 45%, primarily bound to serum albumin). Crosses the blood-brain barrier and placenta; excreted in human milk.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"18,2,0\"><b data-path-to-node=\"18,2,0\" data-index-in-node=\"0\">Biotransformation:<\/b> Extensively metabolised in the liver via two main Cytochrome P450 pathways:<\/p>\n<ul data-path-to-node=\"18,2,1\">\n<li>\n<p data-path-to-node=\"18,2,1,0,0\"><b data-path-to-node=\"18,2,1,0,0\" data-index-in-node=\"0\">CYP3A4 Pathway (Major):<\/b> <span class=\"math-inline\" data-math=\"N\" data-index-in-node=\"24\"><span class=\"katex\"><span class=\"katex-html\" aria-hidden=\"true\"><span class=\"base\"><span class=\"mord mathnormal\">N<\/span><\/span><\/span><\/span><\/span>-demethylation to <b data-path-to-node=\"18,2,1,0,0\" data-index-in-node=\"43\">noroxycodone<\/b> (a weak opioid agonist).<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"18,2,1,1,0\"><b data-path-to-node=\"18,2,1,1,0\" data-index-in-node=\"0\">CYP2D6 Pathway (Minor):<\/b> <span class=\"math-inline\" data-math=\"O\" data-index-in-node=\"24\"><span class=\"katex\"><span class=\"katex-html\" aria-hidden=\"true\"><span class=\"base\"><span class=\"mord mathnormal\">O<\/span><\/span><\/span><\/span><\/span>-demethylation to <b data-path-to-node=\"18,2,1,1,0\" data-index-in-node=\"43\">oxymorphone<\/b> (a potent, active opioid agonist).<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"18,2,1,2,0\">Metabolites undergo subsequent Phase II glucuronide conjugation.<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<li>\n<p data-path-to-node=\"18,3,0\"><b data-path-to-node=\"18,3,0\" data-index-in-node=\"0\">Elimination:<\/b> Excreted predominantly via the kidneys in urine as conjugated metabolites and unchanged parent compound (&lt; 10%). Apparent elimination half-life (<span class=\"math-inline\" data-math=\"t_{1\/2}\" data-index-in-node=\"158\"><span class=\"katex\"><span class=\"katex-html\" aria-hidden=\"true\"><span class=\"base\"><span class=\"mord\"><span class=\"mord mathnormal\">t<\/span><span class=\"msupsub\"><span class=\"vlist-t vlist-t2\"><span class=\"vlist-r\"><span class=\"vlist\"><span class=\"\"><span class=\"sizing reset-size6 size3 mtight\"><span class=\"mord mtight\">1\/2<\/span><\/span><\/span><\/span><span class=\"vlist-s\">\u200b<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span>) of the extended-release formulation is approximately 4.5 to 8 hours.<\/p>\n<\/li>\n<\/ul>\n<h2 data-path-to-node=\"19\">5. Physiological Effects and Adverse Event Spectrum<\/h2>\n<p data-path-to-node=\"20\">Oxycodone depresses central nervous system processing, slows cardiac\/respiratory drive, and delays gastrointestinal transit time.<\/p>\n<h3 data-path-to-node=\"21\">Adverse Drug Reaction Spectrum<\/h3>\n<ul data-path-to-node=\"22\">\n<li>\n<p data-path-to-node=\"22,0,0\"><b data-path-to-node=\"22,0,0\" data-index-in-node=\"0\">Very Common (<span class=\"math-inline\" data-math=\"\\ge 1\/10\" data-index-in-node=\"13\"><span class=\"katex\"><span class=\"katex-html\" aria-hidden=\"true\"><span class=\"base\"><span class=\"mrel\">\u2265<\/span><\/span><span class=\"base\"><span class=\"mord\">1\/10<\/span><\/span><\/span><\/span><\/span>):<\/b> Constipation, nausea, somnolence, dizziness, headache, pruritus.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"22,1,0\"><b data-path-to-node=\"22,1,0\" data-index-in-node=\"0\">Common (<span class=\"math-inline\" data-math=\"\\ge 1\/100\" data-index-in-node=\"8\"><span class=\"katex\"><span class=\"katex-html\" aria-hidden=\"true\"><span class=\"base\"><span class=\"mrel\">\u2265<\/span><\/span><span class=\"base\"><span class=\"mord\">1\/100<\/span><\/span><\/span><\/span><\/span> to <span class=\"math-inline\" data-math=\"&lt;1\/10\" data-index-in-node=\"21\"><span class=\"katex\"><span class=\"katex-html\" aria-hidden=\"true\"><span class=\"base\"><span class=\"mrel\">&lt;<\/span><\/span><span class=\"base\"><span class=\"mord\">1\/10<\/span><\/span><\/span><\/span><\/span>):<\/b> Vomiting, dry mouth, anorexia, abdominal pain, asthenia, fatigue, confusion, anxiety, insomnia, hyperhidrosis, rash.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"22,2,0\"><b data-path-to-node=\"22,2,0\" data-index-in-node=\"0\">Uncommon (<span class=\"math-inline\" data-math=\"\\ge 1\/1,000\" data-index-in-node=\"10\"><span class=\"katex\"><span class=\"katex-html\" aria-hidden=\"true\"><span class=\"base\"><span class=\"mrel\">\u2265<\/span><\/span><span class=\"base\"><span class=\"mord\">1\/1<\/span><span class=\"mpunct\">,<\/span><span class=\"mord\">000<\/span><\/span><\/span><\/span><\/span> to <span class=\"math-inline\" data-math=\"&lt;1\/100\" data-index-in-node=\"25\"><span class=\"katex\"><span class=\"katex-html\" aria-hidden=\"true\"><span class=\"base\"><span class=\"mrel\">&lt;<\/span><\/span><span class=\"base\"><span class=\"mord\">1\/100<\/span><\/span><\/span><\/span><\/span>):<\/b> Respiratory depression, profound sedation, miosis, urinary retention, hallucinations, agitation, euphoria, orthostatic hypotension, physical dependence\/withdrawal.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"22,3,0\"><b data-path-to-node=\"22,3,0\" data-index-in-node=\"0\">Rare \/ Very Rare (&lt;1\/1,000):<\/b> Anaphylactic reactions, paralytic ileus, seizures, opioid-induced hyperalgesia, adrenal insufficiency.<\/p>\n<\/li>\n<\/ul>\n<h2 data-path-to-node=\"23\">6. Contraindications, Drug Interactions, and Clinical Precautions<\/h2>\n<h3 data-path-to-node=\"24\">Contra-indicaties<\/h3>\n<ul data-path-to-node=\"25\">\n<li>\n<p data-path-to-node=\"25,0,0\">Known hypersensitivity to oxycodone or formulation excipients.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"25,1,0\">Significant respiratory depression with hypoxia or hypercapnia.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"25,2,0\">Acute severe bronchial asthma or severe chronic obstructive pulmonary disease (COPD).<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"25,3,0\">Suspected or confirmed paralytic ileus or acute abdomen.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"25,4,0\">Moderate to severe hepatic impairment.<\/p>\n<\/li>\n<\/ul>\n<h3 data-path-to-node=\"26\">Key Drug Interactions<\/h3>\n<ul data-path-to-node=\"27\">\n<li>\n<p data-path-to-node=\"27,0,0\"><b data-path-to-node=\"27,0,0\" data-index-in-node=\"0\">CYP3A4 Inhibitors (e.g., Ketoconazole, Clarithromycin, Ritonavir, Grapefruit Juice):<\/b> Significantly increase oxycodone plasma concentrations, elevating the risk of fatal respiratory depression.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"27,1,0\"><b data-path-to-node=\"27,1,0\" data-index-in-node=\"0\">CYP3A4 Inducers (e.g., Rifampicin, Carbamazepine, St. John&#8217;s Wort):<\/b> Accelerate clearance, reducing analgesic efficacy and potentially precipitating opioid withdrawal.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"27,2,0\"><b data-path-to-node=\"27,2,0\" data-index-in-node=\"0\">CNS Depressants, Benzodiazepines, &amp; Alcohol:<\/b> Co-administration markedly increases the risk of profound sedation, respiratory depression, coma, and death.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"27,3,0\"><b data-path-to-node=\"27,3,0\" data-index-in-node=\"0\">Monoamine Oxidase Inhibitors (MAOIs):<\/b> Caution is required; potential for severe CNS excitation or depression.<\/p>\n<\/li>\n<\/ul>\n<h3 data-path-to-node=\"28\">Clinical Precautions and Monitoring<\/h3>\n<ul data-path-to-node=\"29\">\n<li>\n<p data-path-to-node=\"29,0,0\"><b data-path-to-node=\"29,0,0\" data-index-in-node=\"0\">Boxed Warning (Opioid Analgesic Risk):<\/b> OxyContin exposes users to risks of opioid addiction, abuse, and misuse, which can lead to overdose and death. Assess patient risk prior to prescribing and monitor regularly.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"29,1,0\"><b data-path-to-node=\"29,1,0\" data-index-in-node=\"0\">Opioid Na\u00efvet\u00e9:<\/b> Higher doses or initiation in non-opioid-tolerant individuals carries a substantial risk of fatal respiratory depression.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"29,2,0\"><b data-path-to-node=\"29,2,0\" data-index-in-node=\"0\">Dependence &amp; Withdrawal:<\/b> Prolonged therapy produces physical dependence. Abrupt discontinuation precipitates a severe withdrawal syndrome (diaphoresis, anxiety, lacrimation, rhinorrhea, abdominal cramps, myalgia). Tapering schedules must be implemented when stopping treatment.<\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n\n    <div class=\"xs_social_share_widget xs_share_url after_content \t\tmain_content  wslu-style-1 wslu-share-box-shaped wslu-fill-colored wslu-none wslu-share-horizontal wslu-theme-font-no wslu-main_content\">\n\n\t\t\n        <ul>\n\t\t\t        <\/ul>\n    <\/div>","protected":false},"excerpt":{"rendered":"<p data-path-to-node=\"1\">OxyContin 20 mg (oxycodone hydrochloride extended-release) is a controlled-release, semi-synthetic opioid analgesic indicated for the management of severe, continuous chronic pain requiring around-the-clock long-term opioid therapy.<\/p>\n<h3 data-path-to-node=\"3\">\u00a0<\/h3>","protected":false},"featured_media":6718,"comment_status":"closed","ping_status":"closed","template":"","meta":{"postBodyCss":"","postBodyMargin":[],"postBodyPadding":[],"postBodyBackground":{"backgroundType":"classic","gradient":""}},"product_brand":[],"product_cat":[108],"product_tag":[130],"class_list":["post-6717","product","type-product","status-publish","has-post-thumbnail","product_cat-pain-relief","product_tag-oxycontin-20mg","instock","shipping-taxable","purchasable","product-type-variable"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.5 (Yoast SEO v28.5) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>OxyContin 20mg - British Pharmacy<\/title>\n<meta name=\"description\" content=\"OxyContin 20mg is a prescription opioid medication with oxycodone HCL as its active ingredient, designed to provide long pain relief for up to 12hours.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/bristishpharmacy.co.uk\/nl\/shop\/oxycontin-20mg\/\" \/>\n<meta property=\"og:locale\" content=\"nl_NL\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"OxyContin 20mg\" \/>\n<meta property=\"og:description\" content=\"OxyContin 20 mg (oxycodone hydrochloride extended-release) is a controlled-release, semi-synthetic opioid analgesic indicated for the management of severe, continuous chronic pain requiring around-the-clock long-term opioid therapy.\u00a0\" \/>\n<meta property=\"og:url\" content=\"https:\/\/bristishpharmacy.co.uk\/nl\/shop\/oxycontin-20mg\/\" \/>\n<meta property=\"og:site_name\" content=\"British Pharmacy\" \/>\n<meta property=\"article:modified_time\" content=\"2026-09-16T10:31:40+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/bristishpharmacy.co.uk\/wp-content\/uploads\/2025\/12\/OxyContin-20Mg.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"600\" \/>\n\t<meta property=\"og:image:height\" content=\"450\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Geschatte leestijd\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minuten\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/bristishpharmacy.co.uk\\\/shop\\\/oxycontin-20mg\\\/\",\"url\":\"https:\\\/\\\/bristishpharmacy.co.uk\\\/shop\\\/oxycontin-20mg\\\/\",\"name\":\"OxyContin 20mg - British Pharmacy\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/bristishpharmacy.co.uk\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/bristishpharmacy.co.uk\\\/shop\\\/oxycontin-20mg\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/bristishpharmacy.co.uk\\\/shop\\\/oxycontin-20mg\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/bristishpharmacy.co.uk\\\/wp-content\\\/uploads\\\/2025\\\/12\\\/OxyContin-20Mg.jpeg\",\"datePublished\":\"2025-12-09T01:28:06+00:00\",\"dateModified\":\"2026-09-16T10:31:40+00:00\",\"description\":\"OxyContin 20mg is a prescription opioid medication with oxycodone HCL as its active ingredient, designed to provide long pain relief for up to 12hours.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/bristishpharmacy.co.uk\\\/shop\\\/oxycontin-20mg\\\/#breadcrumb\"},\"inLanguage\":\"nl-NL\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/bristishpharmacy.co.uk\\\/shop\\\/oxycontin-20mg\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"nl-NL\",\"@id\":\"https:\\\/\\\/bristishpharmacy.co.uk\\\/shop\\\/oxycontin-20mg\\\/#primaryimage\",\"url\":\"https:\\\/\\\/bristishpharmacy.co.uk\\\/wp-content\\\/uploads\\\/2025\\\/12\\\/OxyContin-20Mg.jpeg\",\"contentUrl\":\"https:\\\/\\\/bristishpharmacy.co.uk\\\/wp-content\\\/uploads\\\/2025\\\/12\\\/OxyContin-20Mg.jpeg\",\"width\":600,\"height\":450,\"caption\":\"OxyContin 20mg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/bristishpharmacy.co.uk\\\/shop\\\/oxycontin-20mg\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/bristishpharmacy.co.uk\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Shop\",\"item\":\"https:\\\/\\\/bristishpharmacy.co.uk\\\/shop\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"OxyContin 20mg\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/bristishpharmacy.co.uk\\\/#website\",\"url\":\"https:\\\/\\\/bristishpharmacy.co.uk\\\/\",\"name\":\"British Pharmacy\",\"description\":\"Order Medication &amp; Pills Online\",\"publisher\":{\"@id\":\"https:\\\/\\\/bristishpharmacy.co.uk\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/bristishpharmacy.co.uk\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"nl-NL\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/bristishpharmacy.co.uk\\\/#organization\",\"name\":\"British Pharma\",\"url\":\"https:\\\/\\\/bristishpharmacy.co.uk\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"nl-NL\",\"@id\":\"https:\\\/\\\/bristishpharmacy.co.uk\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/bristishpharmacy.co.uk\\\/wp-content\\\/uploads\\\/2026\\\/09\\\/Site-icon.png\",\"contentUrl\":\"https:\\\/\\\/bristishpharmacy.co.uk\\\/wp-content\\\/uploads\\\/2026\\\/09\\\/Site-icon.png\",\"width\":513,\"height\":513,\"caption\":\"British Pharma\"},\"image\":{\"@id\":\"https:\\\/\\\/bristishpharmacy.co.uk\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"OxyContin 20mg - British Pharmacy","description":"OxyContin 20mg is een recept opio\u00efde medicatie met oxycodon HCL alsook met de werkzame stof, bedoeld om te voorzien in lange verlichting van de pijn voor maximaal 12 uur.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/bristishpharmacy.co.uk\/nl\/shop\/oxycontin-20mg\/","og_locale":"nl_NL","og_type":"article","og_title":"OxyContin 20mg","og_description":"OxyContin 20 mg (oxycodone hydrochloride extended-release) is a controlled-release, semi-synthetic opioid analgesic indicated for the management of severe, continuous chronic pain requiring around-the-clock long-term opioid therapy.\u00a0","og_url":"https:\/\/bristishpharmacy.co.uk\/nl\/shop\/oxycontin-20mg\/","og_site_name":"British Pharmacy","article_modified_time":"2026-09-16T10:31:40+00:00","og_image":[{"width":600,"height":450,"url":"https:\/\/bristishpharmacy.co.uk\/wp-content\/uploads\/2025\/12\/OxyContin-20Mg.jpeg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Geschatte leestijd":"3 minuten"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/bristishpharmacy.co.uk\/shop\/oxycontin-20mg\/","url":"https:\/\/bristishpharmacy.co.uk\/shop\/oxycontin-20mg\/","name":"OxyContin 20mg - British Pharmacy","isPartOf":{"@id":"https:\/\/bristishpharmacy.co.uk\/#website"},"primaryImageOfPage":{"@id":"https:\/\/bristishpharmacy.co.uk\/shop\/oxycontin-20mg\/#primaryimage"},"image":{"@id":"https:\/\/bristishpharmacy.co.uk\/shop\/oxycontin-20mg\/#primaryimage"},"thumbnailUrl":"https:\/\/bristishpharmacy.co.uk\/wp-content\/uploads\/2025\/12\/OxyContin-20Mg.jpeg","datePublished":"2025-12-09T01:28:06+00:00","dateModified":"2026-09-16T10:31:40+00:00","description":"OxyContin 20mg is een recept opio\u00efde medicatie met oxycodon HCL alsook met de werkzame stof, bedoeld om te voorzien in lange verlichting van de pijn voor maximaal 12 uur.","breadcrumb":{"@id":"https:\/\/bristishpharmacy.co.uk\/shop\/oxycontin-20mg\/#breadcrumb"},"inLanguage":"nl-NL","potentialAction":[{"@type":"ReadAction","target":["https:\/\/bristishpharmacy.co.uk\/shop\/oxycontin-20mg\/"]}]},{"@type":"ImageObject","inLanguage":"nl-NL","@id":"https:\/\/bristishpharmacy.co.uk\/shop\/oxycontin-20mg\/#primaryimage","url":"https:\/\/bristishpharmacy.co.uk\/wp-content\/uploads\/2025\/12\/OxyContin-20Mg.jpeg","contentUrl":"https:\/\/bristishpharmacy.co.uk\/wp-content\/uploads\/2025\/12\/OxyContin-20Mg.jpeg","width":600,"height":450,"caption":"OxyContin 20mg"},{"@type":"BreadcrumbList","@id":"https:\/\/bristishpharmacy.co.uk\/shop\/oxycontin-20mg\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/bristishpharmacy.co.uk\/"},{"@type":"ListItem","position":2,"name":"Shop","item":"https:\/\/bristishpharmacy.co.uk\/shop\/"},{"@type":"ListItem","position":3,"name":"OxyContin 20mg"}]},{"@type":"WebSite","@id":"https:\/\/bristishpharmacy.co.uk\/#website","url":"https:\/\/bristishpharmacy.co.uk\/","name":"British Pharmacy","description":"Order Medication &amp; Pills Online","publisher":{"@id":"https:\/\/bristishpharmacy.co.uk\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/bristishpharmacy.co.uk\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"nl-NL"},{"@type":"Organization","@id":"https:\/\/bristishpharmacy.co.uk\/#organization","name":"British Pharma","url":"https:\/\/bristishpharmacy.co.uk\/","logo":{"@type":"ImageObject","inLanguage":"nl-NL","@id":"https:\/\/bristishpharmacy.co.uk\/#\/schema\/logo\/image\/","url":"https:\/\/bristishpharmacy.co.uk\/wp-content\/uploads\/2026\/09\/Site-icon.png","contentUrl":"https:\/\/bristishpharmacy.co.uk\/wp-content\/uploads\/2026\/09\/Site-icon.png","width":513,"height":513,"caption":"British Pharma"},"image":{"@id":"https:\/\/bristishpharmacy.co.uk\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/bristishpharmacy.co.uk\/nl\/wp-json\/wp\/v2\/product\/6717","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bristishpharmacy.co.uk\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/bristishpharmacy.co.uk\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/bristishpharmacy.co.uk\/nl\/wp-json\/wp\/v2\/comments?post=6717"}],"version-history":[{"count":5,"href":"https:\/\/bristishpharmacy.co.uk\/nl\/wp-json\/wp\/v2\/product\/6717\/revisions"}],"predecessor-version":[{"id":10791,"href":"https:\/\/bristishpharmacy.co.uk\/nl\/wp-json\/wp\/v2\/product\/6717\/revisions\/10791"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bristishpharmacy.co.uk\/nl\/wp-json\/wp\/v2\/media\/6718"}],"wp:attachment":[{"href":"https:\/\/bristishpharmacy.co.uk\/nl\/wp-json\/wp\/v2\/media?parent=6717"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/bristishpharmacy.co.uk\/nl\/wp-json\/wp\/v2\/product_brand?post=6717"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/bristishpharmacy.co.uk\/nl\/wp-json\/wp\/v2\/product_cat?post=6717"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/bristishpharmacy.co.uk\/nl\/wp-json\/wp\/v2\/product_tag?post=6717"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}